Not available in the U.S.
Hydroquinidine
SERECOR
What it isDihydro derivative of quinidine, a class IA sodium channel blocker; Brugada syndrome and arrhythmia.
Why this oneAlong with quinidine it is one of the few drugs that suppresses ventricular fibrillation in Brugada syndrome.
What limits itQT prolongation and cinchonism as for quinidine. Not US-approved.
FDA-approved for
- cardiac arrhythmias (non-US)
Off-label
- Brugada syndrome
- arrhythmias (approved in France)
NO BOXED WARNINGS
Principal riskQT prolongation and cinchonism
Classes and tags
Clinical profile
Defining liabilityTorsades, conduction block and potentially lethal proarrhythmia