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Hydrocortisone topical

CORTIZONE-10

Pronunciation: hye-droe-KOR-ti-soen

Hydrocortisone topical ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Hydrocortisone topical ballicule

What it isTopical glucocorticoid and mineralocorticoid agonist; mild eczema, dermatitis, and inflammatory itching.

Why this oneIts low potency and OTC availability make it the topical steroid of choice for thin skin and sensitive sites.

What limits itProlonged, occluded, or extensive use causes skin atrophy and can suppress the adrenal axis; infection may be masked.

Hydrocortisone topical molecular structure (skeletal formula)
Molecular structure: Hydrocortisone topical

FDA label

FDA dosingPopulationStartTargetMax
Temporary relief of itching from minor skin irritations, inflammation, and rashes (eczema, psoriasis, seborrheic dermatitis, insect bites, poison ivy/oak/sumac, soaps, detergents, cosmetics, jewelry)Adults & children ≥2 yrApply a thin layer to the affected areaApply a thin layer to the affected area3–4 times daily

Renal Undefined

Hepatic Undefined

Instructions

Available strengths

Contraindications

Cautions

Adverse reactions

Pregnancy Undefined

Lactation Undefined

Cost

Hydrocortisone topical (CORTIZONE-10)
Strength#/mogeneric $/unitCostPlus
0.2 %creamper unitnot offered
1 %creamper unitnot offered
2.5 %creamper unitnot offered
NADAC is a voluntary CMS survey of what retail community pharmacies pay for the drugs they stock. Hydrocortisone topical is dispensed outside retail pharmacies, so it rarely appears on surveyed invoices.

Other forms: Hydrocortisone (CORTEF cortisol)

NO BOXED WARNINGS

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

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