Guanabenz
WYTENSIN
Pronunciation: GWAHN-a-benz
What it isCentral alpha-2 agonist; hypertension.
Why this oneA clonidine-like agent retained where clonidine is not tolerated.
What limits itRebound hypertension on withdrawal, sedation and dry mouth. Now rarely used.
FDA-approved for
- hypertension (1982)
NO BOXED WARNINGS
Principal riskRebound hypertension on withdrawal, sedation and dry mouth
Classes and tags
Clinical profile
Legacy pregnancy categoryC
Defining liabilitySedation, bradycardia and rebound hypertension