Glipizide ER
GLUCOTROL XL
Pronunciation: GLIP-i-zide
What it isSulfonylurea that closes beta-cell KATP channels to release insulin; type 2 diabetes.
Why this oneIts shorter hypoglycemic tail than glyburide makes it a preferred sulfonylurea when kidney function is reduced.
What limits itMissed meals can provoke hypoglycemia; weight gain and progressive beta-cell failure limit durability.
NO BOXED WARNINGS
Principal riskHypoglycemia