Fosinoprilat
from fosinopril
What it isThe active diacid metabolite of fosinopril.
Why it mattersIt is the working ACE inhibitor once esterases strip the prodrug.
What it changesUniquely in the class it clears by both hepatic and renal routes, so fosinopril needs the least renal dose adjustment of the ACE inhibitors.
NO BOXED WARNINGS