Fluticasone nasal
FLONASE
Pronunciation: floo-TIK-a-soen
“Nasal Flo”
What it isLocal glucocorticoid agonist that suppresses nasal inflammation; allergic rhinitis.
Why this oneSystemic exposure is lower than with budesonide or triamcinolone, favoring it when prolonged daily use is expected.
What limits itEpistaxis and septal irritation are technique problems — aim away from the septum. Strong CYP3A4 inhibitors can cause systemic steroid effects.
FDA label
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| FDA dosing | Population | Start | Target | Max |
|---|---|---|---|---|
| Hay fever / upper respiratory allergy symptoms | Adults & children ≥12 yr | Week 1: 2 sprays in each nostril once daily | Weeks 2 through 6 months: 1–2 sprays in each nostril once daily as needed | 2 sprays per nostril once daily |
| Hay fever / upper respiratory allergy symptoms | Children 4–11 yr | 1 spray in each nostril once daily | 1 spray in each nostril once daily (shortest time necessary) | 1 spray per nostril once daily |
Renal Undefined.
Hepatic Undefined.
Instructions
- Use only once a day; do not use more than directed
- Prime the bottle and shake gently before each use
- For use in the nose only; do not spray into eyes or mouth
- Children 4–11 yr: adult supervision; talk to doctor if used longer than 2 months/year
Available strengths
- nasal spray 27.5, 50, 93 mcg/spray
- powder 0.05, 0.1, 0.2, 0.25 mg/inh
- cream 0.05 %
- inhaler 44, 110, 220 mcg/inh
- lotion 0.05 %
- ointment 0.005 %
Contraindications
- Do not use in children under 4 years of age
- Do not use to treat asthma
- Do not use with nasal injury or surgery that is not fully healed
Cautions
- Ask a doctor if you have/had glaucoma or cataracts
- Slower growth rate in some children
- Ask doctor/pharmacist if taking ritonavir, steroid medicine, or ketoconazole
- Stop use for vision changes or frequent nosebleeds
Adverse reactions
- Nasal stinging or sneezing after use
- Nosebleeds
- Slower growth rate in children
- Nasal whistling (sign of nasal damage)
Pregnancy If pregnant, ask a health professional before use.
Lactation If breast-feeding, ask a health professional before use.
Cost
| Strength | #/mo | generic $/unit | CostPlus | |
|---|---|---|---|---|
| 27.5 mcg/spray | nasal spray | per unit | not offered | |
| 50 mcg/spray | nasal spray | per unit | $0.68/mL | offered |
| 93 mcg/spray | nasal spray | per unit | not offered |
Other forms: Fluticasone (FLOVENT)
Available combined with: fluticasone / salmeterol · fluticasone / salmeterol / hfa · fluticasone / umeclidinium / vilanterol · fluticasone / vilanterol
NO BOXED WARNINGS
Classes and tags
Clinical profile
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