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Flunitrazepam

ROHYPNOL

Flunitrazepam ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Flunitrazepam ballicule

What it isA potent intermediate-acting benzodiazepine hypnotic, marketed abroad but never in the United States.

Why this oneIt matters mostly as a hazard: its potency, amnestic effect, and notoriety in drug-facilitated assault made it the emblematic “date-rape” benzodiazepine.

What limits itIn the U.S. it is a trafficked, not prescribed, drug — encountered in toxicology screens rather than pharmacies.

Flunitrazepam molecular structure (skeletal formula)
Molecular structure: Flunitrazepam

NO BOXED WARNINGS

Classes and tags

Clinical profile

Therapeutic safety burden3 / 4
Overdose danger2 / 4
Weight-gain liability0 / 4
Sedation liability3 / 4
QT / Torsades0 / 4
Direct muscarinic antagonism0 / 4
Embryofetal risk2 / 4

Defining liabilitySedation, amnesia, dependence and respiratory depression with other depressants

Active metabolites

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