Fenoldopam
CORLOPAM
“Finn, old, with Coral”
What it isPeripheral dopamine D1-receptor agonist; short-term IV treatment of severe hypertension.
Why this oneIt lowers blood pressure while increasing renal blood flow, a distinctive feature among parenteral antihypertensives.
What limits itReflex tachycardia and increased intraocular pressure limit use; the infusion contains sulfite.
FDA-approved for
- severe hypertension (1997)
NO BOXED WARNINGS
Principal riskReflex tachycardia; raised intraocular pressure
Classes and tags
Clinical profile
Legacy pregnancy categoryB
Defining liabilityRapid hypotension, reflex tachycardia and hypokalemia during infusion