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Ethacizine

ETATSIZIN

Ethacizine ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Ethacizine ballicule

What it isClass IC antiarrhythmic used in Russia.

Why this oneAvailable where other class IC agents are not.

What limits itThe CAST proarrhythmia concern applies to the class. Not US-approved.

Ethacizine molecular structure (skeletal formula)
Molecular structure: Ethacizine

FDA-approved for

Off-label

NO BOXED WARNINGS

Principal riskThe CAST proarrhythmia concern applies to the class

Classes and tags

Clinical profile

Therapeutic safety burden3 / 4
Overdose danger3 / 4
QT / Torsades0 / 4
Direct muscarinic antagonism0 / 4

Defining liabilityProarrhythmia, conduction block and impaired myocardial contractility

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