Enoxacin
PENETREX
What it isFluoroquinolone; bacterial infection.
Why this oneLittle used, but pharmacologically notable as one of the strongest CYP1A2 inhibitors.
What limits itSeizure risk and the full quinolone liability. Largely withdrawn from use.
FDA-approved for
- bacterial infections (1991)
NO BOXED WARNINGS
Principal riskSeizure risk and the full quinolone liability
Classes and tags
Clinical profile
Defining liabilityTendon/CNS toxicity and potent CYP1A2 interactions