Choline
What it isEssential nutrient and the precursor from which acetylcholine is synthesized.
Why this oneSupply can limit acetylcholine synthesis, which is the rationale behind choline-donor supplements.
What limits itSupplement evidence for cognition is weak; the rate-limiting step is usually the transporter, not substrate supply.
Available strengths
- tab 250, 500 mg (bitartrate)
NO BOXED WARNINGS
Principal riskEndogenous or dietary; no boxed warning applies