Biotin

VITAMIN B7

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Biotin ballicule: receptor binding, kinetics and half-life diagram — Mechanism of action: Biotin ballicule

What it isVitamin B7, a carboxylase cofactor; biotinidase deficiency and true deficiency.

Why this oneIt is curative in biotinidase deficiency if started early.

What limits it⚑ Supplements can produce false troponin and thyroid immunoassay results, including missed infarction. Hair and nail benefit is unproven.

Biotin molecular structure (skeletal formula) — Molecular structure: Biotin

FDA-approved for

biotin deficiency

Off-label

biotin deficiency
hair and nail growth (no proven benefit; interferes with immunoassays)

Available strengths

tab/cap 300, 1000, 5000, 10000 mcg

NO BOXED WARNINGS

Principal riskIt skews biotin-based immunoassays, including troponin

Classes and tags

Very short half-life drugs
Vitamins and minerals

Clinical profile

Therapeutic safety burden1 / 4

Overdose danger0 / 4

Direct muscarinic antagonism0 / 4

Active metabolites

Biocytin

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