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Bilobalide

in Ginkgo biloba

Bilobalide ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Bilobalide ballicule

What it isGinkgo biloba constituent and a GABA-A negative allosteric modulator.

Why this oneIts GABA-A antagonism is one proposed route by which ginkgo may lower the seizure threshold.

What limits itIt is why ginkgo is best avoided in epilepsy despite being sold freely.

Bilobalide molecular structure (skeletal formula)
Molecular structure: Bilobalide

FDA-approved for

NO BOXED WARNINGS

Principal riskIt may lower the seizure threshold

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

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