Not available in the U.S.
Atosiban
TRACTOCILE
What it isOxytocin and V1a antagonist; tocolysis in preterm labor.
Why this oneIt suppresses contractions with far fewer maternal cardiovascular effects than beta agonists.
What limits itIt delays delivery without clearly improving neonatal outcome. Not US-approved.
FDA-approved for
- preterm labor (non-US)
Off-label
- tocolysis for preterm labor (approved in Europe)
NO BOXED WARNINGS
Principal riskIt delays delivery without clearly improving neonatal outcome