ASA
Pronunciation: AS-pir-in


What it isIrreversible COX-1 and COX-2 inhibitor; secondary cardiovascular prevention, acute coronary syndrome and stroke.
Why this oneIts irreversible platelet effect persists for each platelet's lifespan, distinguishing it from other NSAIDs.
What limits itGI bleeding limits use; primary prevention rarely justifies it. Avoid in viral illness in children; ibuprofen taken first blunts platelet effect.
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| FDA dosing | Population | Start | Target | Max |
|---|---|---|---|---|
| Not stated in fetched sections (OTC analgesic/antipyretic label — Uses/Purpose section absent) | Adults & children ≥12 yr | 4 tablets q4h PRN | 4–8 tablets q4h PRN while symptoms last | 48 tablets/24 h |
Renal Undefined
Hepatic Undefined
Dose expressed in tablets only — tablet strength (mg) is not stated in any fetched section.
Available strengths
Pregnancy Undefined
Lactation Undefined
| Strength | #/mo | generic $/unit | CostPlus | |
|---|---|---|---|---|
| 81 mg | tab | per unit | $0.01/ea | offered |
| 325 mg | tab | per unit | $0.02/ea | not offered |
| 500 mg | tab | per unit | not offered |
NO BOXED WARNINGS
Principal riskGI bleeding, and Reye syndrome in children
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