Aldosterone
endogenous
“Al-Dough stir own”
bananas dispersing → decreased serum potassium
retention of whater and sodium
What it isThe endogenous mineralocorticoid driving sodium retention and potassium excretion.
Why this oneIt is the target of spironolactone, eplerenone and finerenone, and the reason those drugs cause hyperkalemia.
What limits itIts escape from ACE-inhibitor suppression is why an MRA is added in heart failure rather than relying on RAAS blockade alone.
NO BOXED WARNINGS
Principal riskEndogenous or dietary; no boxed warning applies