charcoal

What it isNonabsorbed toxin sequestrant that adsorbs many drugs in the gut; selected acute oral poisonings.
Why this oneIt can broadly reduce absorption when given promptly, unlike antidotes that target only one toxin.
What limits it⚑ It does not bind iron, lithium, alcohols, or hydrocarbons; aspiration can be lethal, so withhold if the airway is unprotected.
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| FDA dosing | Population | Start | Target | Max |
|---|---|---|---|---|
| Emergency adsorption of swallowed poisons | All (as directed by a health professional) | 20–30 g PO in ≥8 oz liquid ×1 | 20–30 g; repeat dose immediately if possible | Undefined |
Renal Undefined
Hepatic Undefined
Available strengths
Pregnancy Undefined
Lactation Undefined
| Strength | #/mo | generic $/unit | CostPlus | |
|---|---|---|---|---|
| 25 g/240 mL | susp | per unit | not offered | |
| 208 mg/mL | susp | per unit | not offered |
NO BOXED WARNINGS
Principal riskUseless for iron, lithium, alcohols and hydrocarbons
Defining liabilityAspiration injury; gastrointestinal obstruction